Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809089 | 0.85 | GSK3A (0.41) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9809097 | 0.83 | GSK3A (0.40) | MAPTALDH1A1HPGDGSK3AGSK3B | |
| SCHEMBL11611721 | 0.79 | GSK3A (0.45) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3882745 | 0.78 | CYP19A1 (0.56) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL536896 | 0.77 | CYP19A1 (0.55) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9809062 | 0.76 | CYP19A1 (0.38) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9809111 | 0.73 | CYP19A1 (0.37) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9809125 | 0.72 | CYP19A1 (0.44) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9809064 | 0.72 | NOX4 (0.45) | MAPTALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL9809107 | 0.70 | CYP19A1 (0.43) | MAPTALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |