Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 3/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695144 | 0.89 | ALDH1A1 (0.44) | MAOBALDH1A1MEN1KMT2APTPRC | |
| SCHEMBL29634280 | 0.81 | KDM4E (0.44) | MAOBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL28523595 | 0.81 | KDM4E (0.44) | MAOBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6736201 | 0.80 | MAOB (0.63) | MAOBALDH1A1ACHE | |
| SCHEMBL14707700 | 0.79 | NR3C1 (0.50) | MAOBKMT2ARAB9AGAAMAPT | |
| SCHEMBL28524800 | 0.77 | KDM4E (0.43) | MAOBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL29634193 | 0.77 | KDM4E (0.43) | MAOBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6739190 | 0.75 | MAOB (0.59) | MAOB | |
| SCHEMBL6737854 | 0.75 | MAOB (0.59) | MAOB | |
| SCHEMBL28525296 | 0.75 | KDM4E (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394155-B1 | Process for the preparation of 5-Nitrobenzofurans | LANXESS DEUTSCHLAND GMBH (DE) | 2006-06-28 | — | — | EP | claimed |
| US-20050288519-A1 | 5-Nitrobenzofurans | MAGERLEIN WOLFGANG | 2005-12-29 | — | — | US | claimed |
| EP-1394155-A2 | 5-Nitrobenzofuranes | Bayer Chemicals AG (DE) | 2004-03-03 | — | — | EP | claimed |
| US-20040034220-A1 | 5-Nitrobenzofurans | LANXESS DEUTSCHLAND GMBH (DE) | 2004-02-19 | — | — | US | claimed |
| CN-102070577-B | 2-normal-butyl-3-(4-replaces propoxy-benzoyl)-5-substituted-amino cumarone and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-03-09 | — | — | CN | disclosed |
| CN-102070577-A | 2-n-butyl-3-(4-subsitituted propylbenzoyl)-5-substituted amino benzofuran and application thereof | SHANGHAI INST PHARM INDUSTRY | 2011-05-25 | — | — | CN | disclosed |
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | FINORGA | 2011-01-13 | — | — | US | disclosed |
| CN-101687764-A | Method for preparing 2-(n-butyl)-5-nitrobenzofuran | FINORGA | 2010-03-31 | — | — | CN | disclosed |
| EP-2144866-A1 | METHOD FOR PREPARING 2-(N-BUTYL)-5-NITROBENZOFURAN | Finorga (FR) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008152217-A2 | PROCESS FOR PREPARING 2-(N-BUTYL)-5-NITROBENZOFURAN | FINORGA (FR) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008139056-A1 | METHOD FOR PREPARING 2-(N-BUTYL)-5-NITROBENZOFURAN | FINORGA (FR) | 2008-11-20 | — | — | WO | disclosed |
| EP-1394155-B1 | Process for the preparation of 5-Nitrobenzofurans | LANXESS DEUTSCHLAND GMBH (DE) | 2006-06-28 | — | — | EP | disclosed |
| US-6984741-B2 | 5-Nitrobenzofurans | BAYER AKTIENGESELLSCHAFT (DE) | 2006-01-10 | — | — | US | disclosed |
| US-20050288519-A1 | 5-Nitrobenzofurans | MAGERLEIN WOLFGANG | 2005-12-29 | — | — | US | disclosed |
| CN-1485323-A | 5-nitrobenzofurans | — | 2004-03-31 | — | — | CN | disclosed |
| EP-1394155-A2 | 5-Nitrobenzofuranes | Bayer Chemicals AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-20040034220-A1 | 5-Nitrobenzofurans | LANXESS DEUTSCHLAND GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288519-A1 | 5-Nitrobenzofurans | NOX5, NQO1, NDUFS5 | MAOB 119/4885ALDH1A1 233/4885MEN1 3582/4885 |
| US-20040034220-A1 | 5-Nitrobenzofurans | NOX5, NQO1, NDUFS5 | MAOB 119/4885ALDH1A1 233/4885MEN1 3582/4885 |
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | CYP8B1, NISCH, CBR3 | MAOB 110/4885ALDH1A1 903/4885MEN1 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.