SCHEMBL9809190

SCHEMBL9809190

C=CO[SiH](C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052784 0.77 ALDH1A1 (0.33) ALDH1A1TSHRTRPA1
SCHEMBL28312809 0.76 CA4 (0.31)
SCHEMBL288582 0.73 CA4 (0.32) TSHR
Vinyl Ether SCHEMBL28084905 0.72
SCHEMBL28181150 0.72 MEN1 (0.37) ALDH1A1TSHR
SCHEMBL1147891 0.72 CA4 (0.35) ALDH1A1TSHRTRPA1
SCHEMBL17328006 0.72 CA4 (0.35) ALDH1A1TSHRTRPA1
SCHEMBL7208911 0.71
SCHEMBL28077162 0.71 NPC1 (0.30)
SCHEMBL288583 0.70 CA4 (0.39) ALDH1A1TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075038-A Polysiloxanes containing silver flakes DOW CORNING CORPORATION (US) 1991-12-24 US disclosed
EP-0165806-B1 SILYLATED VINYL ALCOHOL POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-29 EP disclosed
EP-0367562-A2 Electrically conductive silicone compositions DOW CORNING CORPORATION (US) 1990-05-09 EP disclosed
EP-0165806-A2 Silylated vinyl alcohol polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-27 EP disclosed
US-4544724-A REACTING ETHENOXYSILANE AND ALDEHYDE, POLYMERIZATION, THEN HYDROLYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-01 US disclosed