SCHEMBL288582

SCHEMBL288582

[CH2]O[SiH](C)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.32
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17328006 0.78 CA4 (0.35) CA4LMNATSHRALOX12ACHE
SCHEMBL1147891 0.78 CA4 (0.35) CA4LMNATSHRALOX12ACHE
SCHEMBL288583 0.76 CA4 (0.39) CA4LMNATSHRALOX12ACHE
SCHEMBL36085 0.74 TSHR (0.32) CA4LMNATSHRALOX12ACHE
SCHEMBL21112786 0.74 CA4 (0.32) CA4LMNATSHRALOX12ACHE
SCHEMBL9721251 0.74 TSHR (0.32) CA4LMNATSHRALOX12ACHE
SCHEMBL1679847 0.74 CA4 (0.32) CA4LMNATSHRALOX12ACHE
SCHEMBL9809190 0.73 ALDH1A1 (0.33) TSHR
SCHEMBL28726334 0.73 PAX8 (0.32)
SCHEMBL22440483 0.72 LTA4H (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427466-A1 PROCESS FOR PRODUCING A PARTICULATE NANOCOMPOSITE MATERIAL BASF SE (DE) 2012-03-14 EP disclosed
EP-2414457-A1 METHOD FOR THE PRODUCTION OF COMPOSITE MATERIALS BASF SE (DE) 2012-02-08 EP disclosed
WO-2010128144-A1 PROCESS FOR PRODUCING A PARTICULATE NANOCOMPOSITE MATERIAL BASF SE (DE) 2010-11-11 WO disclosed
WO-2010112581-A1 METHOD FOR THE PRODUCTION OF COMPOSITE MATERIALS BASF SE (DE) 2010-10-07 WO disclosed