Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380418 | 0.89 | ALOX5 (0.58) | ALOX5HTR2CKDM1AMAOAMAOB | |
| SCHEMBL9380414 | 0.89 | ALOX5 (0.58) | ALOX5HTR2CKDM1AMAOAMAOB | |
| SCHEMBL9381954 | 0.84 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9381956 | 0.84 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9387465 | 0.81 | ALOX5 (0.55) | ALOX5HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9387460 | 0.81 | ALOX5 (0.55) | ALOX5HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9381473 | 0.78 | ALOX5 (0.58) | ALOX5HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9385609 | 0.78 | ALOX5 (0.52) | ALOX5HTR2CKMT2A | |
| SCHEMBL9385605 | 0.78 | ALOX5 (0.52) | ALOX5HTR2CKMT2A | |
| SCHEMBL9381471 | 0.78 | ALOX5 (0.58) | ALOX5HTR2CSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037853-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1991-08-06 | — | — | US | disclosed |