Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | HRH2 | P25021 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809319 | 0.85 | HRH1 (0.69) | HRH1HRH2DRD2HTR2ADRD3 | |
| SCHEMBL9809323 | 0.84 | HRH1 (0.56) | HRH1HRH2DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9809309 | 0.84 | HRH1 (0.68) | HRH1HRH2DRD2HTR2ADRD3 | |
| SCHEMBL9809265 | 0.82 | HRH1 (0.63) | HRH1HRH2DRD2HTR2ADRD3 | |
| SCHEMBL9809242 | 0.81 | HRH1 (0.64) | HRH1HRH2DRD2HTR2ADRD3 | |
| SCHEMBL9809257 | 0.81 | TP53 (0.61) | HRH1HRH2DRD2HTR2ADRD3 | |
| SCHEMBL9809391 | 0.81 | FAAH (0.63) | HRH1HRH2DRD2HTR2ADRD3 | |
| SCHEMBL9809311 | 0.80 | HRH2 (0.63) | HRH1HRH2DRD2HTR2ADRD3 | |
| SCHEMBL9809351 | 0.79 | HRH2 (0.69) | HRH1HRH2DRD2HTR2ALMNA | |
| SCHEMBL9809250 | 0.79 | HRH1 (0.59) | HRH1HRH2DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211928-B1 | PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN | AB LEO (SE) | 1991-05-02 | — | — | EP | disclosed |