Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 10/20 | 0.51 |
| ▸ | DRD3 | P35462 | 10/20 | 0.51 |
| ▸ | HTR1A | P08908 | 9/20 | 0.51 |
| ▸ | HTR2A | P28223 | 9/20 | 0.51 |
| ▸ | DRD1 | P21728 | 5/20 | 0.51 |
| ▸ | DRD5 | P21918 | 5/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9809264 | 0.99 | MEN1 (0.65) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL9809300 | 0.88 | DRD2 (0.53) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL9809319 | 0.82 | HRH1 (0.69) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9809309 | 0.81 | HRH1 (0.68) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL10507988 | 0.80 | TSHR (0.67) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10935509 | 0.80 | MEN1 (0.68) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Amperozide SCHEMBL340961 | 0.79 | CYP3A4 (1.00) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10508822 | 0.79 | TSHR (0.69) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10936666 | 0.79 | MEN1 (0.67) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL9809242 | 0.78 | HRH1 (0.64) | MAPK1FAAHCYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211928-B1 | PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN | AB LEO (SE) | 1991-05-02 | — | — | EP | claimed |