Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | DRD3 | P35462 | 7/20 | 0.58 |
| ▸ | HTR1A | P08908 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 6/20 | 0.58 |
| ▸ | HRH1 | P35367 | 6/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 5/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | DRD5 | P21918 | 4/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809297 | 0.86 | HRH1 (0.63) | USP2ALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL1728918 | 0.85 | USP2 (0.78) | USP2ALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL9809305 | 0.83 | USP2 (0.59) | USP2ALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL13698800 | 0.82 | USP2 (0.73) | USP2ALDH1A1HPGDDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9809253 | 0.82 | ALDH1A1 (0.58) | USP2ALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL24324269 | 0.81 | USP2 (0.68) | USP2ALDH1A1HPGDDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1730768 | 0.81 | USP2 (0.71) | USP2ALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL9809294 | 0.80 | HRH1 (0.64) | USP2ALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL12359053 | 0.79 | USP2 (0.91) | USP2ALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL10510536 | 0.79 | HTR1A (0.54) | DRD2DRD3HTR1AHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211928-B1 | PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN | AB LEO (SE) | 1991-05-02 | — | — | EP | disclosed |