Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776619 | 0.88 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2NPC1USP2RAB9A | |
| SCHEMBL9682404 | 0.87 | GAA (0.45) | SMN1; SMN2NPC1TSHRPOLBALDH1A1 | |
| SCHEMBL8008875 | 0.85 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2NPC1USP2RAB9A | |
| SCHEMBL10913509 | 0.85 | CA2 (0.40) | HSD17B10SMN1; SMN2NPC1USP2RAB9A | |
| SCHEMBL4392652 | 0.84 | MAPT (0.39) | HSD17B10SMN1; SMN2NPC1USP2RAB9A | |
| SCHEMBL8951874 | 0.82 | CA2 (0.39) | HSD17B10SMN1; SMN2TSHRPOLBALDH1A1 | |
| SCHEMBL9558895 | 0.82 | CA2 (0.46) | HSD17B10TSHRPOLBALDH1A1HPGD | |
| SCHEMBL11670686 | 0.76 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2NPC1USP2RAB9A | |
| SCHEMBL11313793 | 0.76 | SMN1; SMN2 (0.48) | HSD17B10SMN1; SMN2NPC1USP2RAB9A | |
| SCHEMBL9750152 | 0.75 | LMNA (0.31) | HSD17B10MAPTTSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015731-A | For fibers such as wool and cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4564672-A | Water-soluble monoazo and disazo compounds containing a fibre-reactive 2-alkoxy-5-chloro-aniline diazo component and copper complexes thereof, useful as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-14 | — | — | US | disclosed |
| EP-0167219-A1 | Fiber-reactive compound having both pyridiniotriazinyl and vinylsulfone type groups | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-01-08 | — | — | EP | disclosed |
| EP-0099721-A1 | Reactive metal formazan blue dye | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-02-01 | — | — | EP | disclosed |