Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809468 | 1.00 | KEAP1 (0.46) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL9618869 | 0.82 | KEAP1 (0.49) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL9809517 | 0.81 | KEAP1 (0.38) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL4883114 | 0.80 | KEAP1 (0.50) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL5948356 | 0.78 | SSTR4 (0.40) | KEAP1NFE2L2 | |
| SCHEMBL5948488 | 0.78 | SSTR4 (0.40) | KEAP1NFE2L2 | |
| SCHEMBL2763726 | 0.75 | KEAP1 (0.56) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL13865471 | 0.74 | KEAP1 (0.54) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL17739911 | 0.74 | KEAP1 (0.54) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL9809511 | 0.73 | KEAP1 (0.72) | KEAP1NFE2L2POLBCHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036107-A | Treatment of neurogenic bladder disorders | MARION MERRELL DOW INC. (US) | 1991-07-30 | — | — | US | disclosed |