Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809542 | 0.84 | KEAP1 (0.40) | KEAP1NFE2L2POLBCHRM2CHRM1 | |
| SCHEMBL9809468 | 0.81 | KEAP1 (0.46) | KEAP1NFE2L2POLBCHRM2CHRM1 | |
| SCHEMBL9809488 | 0.81 | KEAP1 (0.46) | KEAP1NFE2L2POLBCHRM2CHRM1 | |
| SCHEMBL9618819 | 0.78 | KEAP1 (0.57) | KEAP1NFE2L2POLBCHRM2CHRM1 | |
| SCHEMBL5948356 | 0.69 | SSTR4 (0.40) | KEAP1NFE2L2 | |
| SCHEMBL5948488 | 0.69 | SSTR4 (0.40) | KEAP1NFE2L2 | |
| SCHEMBL9619021 | 0.68 | CHRM2 (0.58) | POLBCHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL2763726 | 0.67 | KEAP1 (0.56) | KEAP1NFE2L2POLBCHRM2CHRM1 | |
| SCHEMBL7919594 | 0.67 | KEAP1 (0.56) | KEAP1NFE2L2POLBCHRM2CHRM1 | |
| SCHEMBL7276873 | 0.67 | KEAP1 (0.56) | KEAP1NFE2L2POLBCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036107-A | Treatment of neurogenic bladder disorders | MARION MERRELL DOW INC. (US) | 1991-07-30 | — | — | US | disclosed |