Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 7/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437789 | 0.88 | CACNA1D (0.55) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL7433647 | 0.82 | ADORA3 (0.47) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL7434861 | 0.81 | MAPT (0.43) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL7426346 | 0.81 | CACNA1C (0.47) | CACNA1CADORA3CYP1A2ABCB11OPRM1 | |
| SCHEMBL7428014 | 0.81 | CACNA1C (0.56) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL7435874 | 0.79 | ADORA3 (0.54) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL10615431 | 0.79 | CACNA1C (0.53) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL9809443 | 0.78 | ADORA3 (0.49) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL10614837 | 0.77 | TBXA2R (0.58) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 | |
| SCHEMBL9809444 | 0.76 | HIF1A (0.71) | CACNA1CCACNA1DCACNA1FCACNA1SADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075324-A | ARALKYL-1,4-DIHYDROPYRIDINES, A METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-12-24 | — | — | US | disclosed |