Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | GAA | P10253 | 2/20 | 0.79 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.79 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | G6PC1 | P35575 | 9/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809673 | 1.00 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL130652 | 0.90 | ALDH1A1 (0.78) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8499120 | 0.89 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL3869799 | 0.89 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8499122 | 0.89 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL3869803 | 0.89 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11238432 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11238435 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL14438171 | 0.86 | MEN1 (0.68) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL17454554 | 0.85 | MAPT (0.71) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272793-B | Method for synthesizing aryl hydrazone | 南京理工大学 | 2017-02-15 | — | — | CN | disclosed |
| CN-105272793-A | Method for synthesizing aryl hydrazone | UNIV NANJING SCIENCE & TECH | 2016-01-27 | — | — | CN | disclosed |
| US-RE33719-E | Sweetened edible formulations | BIOSPHERICS INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |
| US-4262032-A | L-HEXOSE MONOSACCHARIDES | BIOSPHERICS INCORPORATED (US) | 1981-04-14 | — | — | US | disclosed |