SCHEMBL130652

SCHEMBL130652

C(=NN(Cc1ccccc1)c1ccccc1)c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.78
KMT2A Q03164 7/20 0.78
MEN1 O00255 6/20 0.78
SMN1; SMN2 Q16637 2/20 0.78
MCL1 Q07820 1/20 0.78
MAPT P10636 9/20 0.75
GAA P10253 2/20 0.75
HSP90AA1 P07900 1/20 0.75
MAPK1 P28482 6/20 0.61
LMNA P02545 6/20 0.61
POLB P06746 2/20 0.61
PKM P14618 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.56
ATM Q13315 1/20 0.56
G6PC1 P35575 8/20 0.55
KDM4E B2RXH2 3/20 0.55
TDP1 Q9NUW8 2/20 0.44
MITF O75030 1/20 0.44
HPGD P15428 1/20 0.44
RAD52 P43351 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9809673 0.90 MAPT (0.79) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL9809671 0.90 MAPT (0.79) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL1702643 0.88 ALDH1A1 (0.74) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL1056798 0.88 ALDH1A1 (0.74) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL10145000 0.87 ALDH1A1 (0.77) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL14337651 0.87 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL11238435 0.86 MAPT (1.00) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL11238432 0.86 MAPT (1.00) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL8499122 0.86 MAPT (0.73) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1
SCHEMBL8499120 0.86 MAPT (0.73) ALDH1A1KMT2AMEN1SMN1; SMN2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103242167-B Amine compound, photoelectric conductor for electronic photography, image forming method, image forming apparatus and handle box RICOH CO., LTD. (JP) 2016-02-24 CN disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 US disclosed
US-20150079509-A1 PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2015-03-19 US disclosed
US-8889324-B2 Image bearing member, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-11-18 US disclosed
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
US-8586270-B2 Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus RICOH COMPANY, LTD. (JP) 2013-11-19 US disclosed
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-08-08 US disclosed
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US disclosed
US-4808503-A SENSITIVITY, DURABILITY MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-28 US disclosed
EP-0270685-A1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-15 EP disclosed
EP-0259099-A2 Electrophotographic photoreceptor MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-09 EP disclosed
US-4716220-A CHARGE CARRIER GENERATING MATERIALS RICOH CO., LTD. (JP) 1987-12-29 US disclosed
US-4708921-A Photosensitive material containing disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1987-11-24 US disclosed
US-4672149-A PHOTOACTIVE LAYER CONTAINING A DISAZO PIGMENT; SOLAR CELLS; EFFICIENCY RICOH CO., LTD. (JP) 1987-06-09 US disclosed
US-4663442-A ELECTROGRAPHY, PHOTOSENSITIVITY RICOH CO., LTD. (JP) 1987-05-05 US disclosed
US-4619878-A Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1986-10-28 US disclosed
US-4582771-A Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography RICOH CO., LTD. (JP) 1986-04-15 US disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE ARL1, ATXN2L, AHR ALDH1A1 1094/4885KMT2A 2164/4885MEN1 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.