Thiourea

Thiourea

SCHEMBL9809709

NC(N)=S.O=C1C=CC(=O)N1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.65
GSK3B P49841 1/20 0.65
CCR6 P51684 1/20 0.65
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
ATR Q13535 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL8556796 0.85 GSK3A (0.69) GSK3AGSK3BCCR6
Thiosemicarbazide SCHEMBL4330062 0.85 GSK3A (0.52) GSK3AGSK3BCCR6
Hydroxyamine SCHEMBL27087760 0.84
Carbamic Acid SCHEMBL6022388 0.82 GSK3A (0.65) GSK3AGSK3BCCR6TSHR
Hydrazine SCHEMBL3175189 0.81
SCHEMBL28058947 0.81
SCHEMBL9989664 0.81
SCHEMBL715867 0.80 GSK3B (1.00) GSK3AGSK3BCCR6
SCHEMBL10990 0.80
SCHEMBL1599522 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5045233-A Storage stability NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1991-09-03 US disclosed