Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809883 | 0.85 | MAPT (0.47) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL13123954 | 0.83 | MAPT (0.46) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL30529006 | 0.77 | ALOX5 (0.46) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL28731386 | 0.77 | MEN1 (0.51) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL9731627 | 0.77 | ALOX5 (0.46) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL7199545 | 0.76 | MTNR1A (0.66) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL4315603 | 0.74 | MEN1 (0.49) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL13990707 | 0.74 | MEN1 (0.49) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL3277849 | 0.73 | MEN1 (0.68) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL432482 | 0.72 | MEN1 (0.66) | MAPTMEN1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004744-A | Durability; effectiveness at low concentration | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | disclosed |
| EP-0373425-A2 | Substituted pyridazinones, their preparation method and their use as insecticides | BAYER AG (DE) | 1990-06-20 | — | — | EP | disclosed |