Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.39 |
| ▸ | RXRB | P28702 | 8/20 | 0.39 |
| ▸ | RXRG | P48443 | 6/20 | 0.39 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14508866 | 0.90 | TP53 (0.37) | RXRARXRBRXRGNR5A2NR5A1 | |
| SCHEMBL462662 | 0.82 | ALDH1A1 (0.49) | NR5A2NR5A1ALDH1A1LMNACYP3A4 | |
| SCHEMBL28133552 | 0.78 | RXRA (0.40) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL1719554 | 0.77 | NR5A2 (0.48) | RXRANR5A2NR5A1ALDH1A1LMNA | |
| SCHEMBL28003878 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1LMNATDP1SMN1; SMN2MEN1 | |
| SCHEMBL7212876 | 0.76 | CYP1A2 (0.42) | RXRARXRBHDAC2HDAC8CYP1A2 | |
| SCHEMBL27594317 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNASLC13A5ESR1ESR2 | |
| SCHEMBL1487540 | 0.74 | BLM (0.51) | ALDH1A1LMNAESR1ESR2CYP3A4 | |
| SCHEMBL3184779 | 0.73 | SLC13A5 (0.43) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL28987895 | 0.73 | RXRA (0.45) | RXRARXRBRXRGLMNASLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030243-A | Applying to a polyamide/polyurethane web an aqueous liquid containing a 2,6-dimethyl-2,6-dialkylpiperidin-4-yl ether, ester or similar derivative | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |