Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ELANE | P08246 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273480 | 0.81 | LMNA (0.47) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL11669502 | 0.80 | LMNA (0.57) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL11851547 | 0.78 | HSD17B10 (0.57) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL1968508 | 0.77 | LMNA (0.53) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| Hydrogen Peroxide SCHEMBL9578945 | 0.76 | LMNA (0.57) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL28212193 | 0.76 | LMNA (0.57) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL24747284 | 0.75 | LMNA (0.62) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL15700661 | 0.75 | LMNA (0.61) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL11349127 | 0.75 | LMNA (0.52) | MAPTGAAALDH1A1HSP90AA1LMNA | |
| SCHEMBL11451243 | 0.75 | MAPT (0.56) | MAPTGAAALDH1A1HSP90AA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255695-B1 | P-HYDROXYCINNAMAMIDE DERIVATIVES AND MELANIN INHIBITOR COMPRISING THE SAME | Kao Corporation (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4981680-A | P-hydroxycinnamamide derivatives and melanin inhibitor comprising the same | KAO CORPORATION (JP) | 1991-01-01 | — | — | US | disclosed |
| US-4876084-A | FOR SPOTS, FRECKLES AND SUNBURN | KAO CORPORATION (JP) | 1989-10-24 | — | — | US | disclosed |
| EP-0255695-A2 | p-Hydroxycinnamamide derivatives and melanin inhibitor comprising the same | Kao Corporation (JP) | 1988-02-10 | — | — | EP | disclosed |