SCHEMBL11669502

SCHEMBL11669502

CC(=O)Oc1ccc(C(Cl)Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
MAPT P10636 3/20 0.52
POLB P06746 2/20 0.52
PKM P14618 1/20 0.52
KDM4E B2RXH2 4/20 0.50
ELANE P08246 3/20 0.50
CYP3A4 P08684 3/20 0.50
ESR1 P03372 3/20 0.50
SLC6A3 Q01959 2/20 0.50
HIF1A Q16665 2/20 0.50
ABCB11 O95342 1/20 0.50
ADRA2A P08913 1/20 0.50
CYP2C9 P11712 1/20 0.50
TSHR P16473 1/20 0.50
PDE4A P27815 1/20 0.50
ADRA1A P35348 1/20 0.50
OPRK1 P41145 1/20 0.50
STAT6 P42226 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15700661 0.83 LMNA (0.61) LMNAMAPTPOLBPKMKDM4E
SCHEMBL24747284 0.83 LMNA (0.62) LMNAMAPTPOLBPKMKDM4E
SCHEMBL269329 0.82 LMNA (0.80) LMNAMAPTPOLBPKMKDM4E
SCHEMBL30943786 0.81 LMNA (0.50) LMNAMAPTPOLBPKMKDM4E
SCHEMBL9506851 0.81 LMNA (0.59) LMNAMAPTPOLBPKMKDM4E
SCHEMBL11603976 0.81 LMNA (0.59) LMNAMAPTPOLBPKMKDM4E
SCHEMBL8055232 0.81 LMNA (0.59) LMNAMAPTPOLBPKMKDM4E
SCHEMBL1714626 0.81 LMNA (0.59) LMNAMAPTPOLBPKMKDM4E
SCHEMBL31173886 0.80 LMNA (0.48) LMNAMAPTPOLBPKMKDM4E
SCHEMBL9810212 0.80 MAPT (0.49) LMNAMAPTPOLBPKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-52153925-A None JP disclosed
JP-52156826-A None JP disclosed
JP-S52156826-A PREPARATION OF P-HYDROXYBENZALDEHYDE KUREHA CHEM IND CO LTD 1977-12-27 JP disclosed
JP-S52153925-A P-ACETOXYBENZYLIDENE CHLORIDE KUREHA CHEM IND CO LTD 1977-12-21 JP disclosed