SCHEMBL9810334

SCHEMBL9810334

CCCC(C)COC(=O)C1=CCC(c2ccc(OC)cc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 3/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
DRD2 P14416 1/20 0.37
HTT P42858 1/20 0.35
GPR88 Q9GZN0 4/20 0.35
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
ADRB3 P13945 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KMT2A Q03164 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810315 0.88 CCR1 (0.37) ALDH1A1MAPTSMN1; SMN2GAALMNA
SCHEMBL9810680 0.85 CYP2C9 (0.45) ALDH1A1MAPTLMNAGPR88KMT2A
SCHEMBL9810677 0.85 CYP2C9 (0.45) ALDH1A1MAPTLMNAGPR88KMT2A
SCHEMBL9810445 0.85 RAB9A (0.39) LMNA
SCHEMBL9810329 0.85 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2GAAKDM4E
SCHEMBL9810275 0.85 SPHK1 (0.40)
SCHEMBL9810509 0.84 ALDH1A1 (0.43) ALDH1A1MAPTSMN1; SMN2GAAKDM4E
SCHEMBL9810695 0.83 ALDH1A1 (0.42) ALDH1A1MAPTSMN1; SMN2GAAKDM4E
SCHEMBL9810377 0.83 CYP2C9 (0.42) ALDH1A1MAPTLMNAGPR88KMT2A
SCHEMBL9810382 0.83 CYP2C9 (0.42) ALDH1A1MAPTLMNAGPR88KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068389-A TERTIARY ALCOHOLS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed