SCHEMBL9810372

SCHEMBL9810372

CC(C)OC(=O)C1=CCC(c2ccc(Cl)cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 2/20 0.39
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
ABCC1 P33527 1/20 0.36
CCR1 P32246 1/20 0.36
IDO1 P14902 1/20 0.36
HPGD P15428 1/20 0.36
PROKR1 Q8TCW9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810290 0.86 SLC6A3 (0.41) SLC6A4SLC6A3NPSR1MEN1KMT2A
SCHEMBL9810308 0.85 SLC6A3 (0.45) SRD5A1SLC6A3NPSR1POLBHPGD
SCHEMBL9810271 0.83 ABCC1 (0.49) SRD5A1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL9810381 0.82 ALDH1A1 (0.43) SRD5A1SLC6A4SLC6A3KMT2ACCR1
SCHEMBL9810282 0.81 CYP2C9 (0.49) MEN1KMT2AIDO1
SCHEMBL9810278 0.81 CYP2C9 (0.49) MEN1KMT2AIDO1
SCHEMBL9810353 0.80 ABCC1 (0.40) SRD5A1NPSR1SMN1; SMN2ABCC1HPGD
SCHEMBL9810315 0.79 CCR1 (0.37) SRD5A1NPSR1SMN1; SMN2ABCC1CCR1
SCHEMBL9810593 0.78 CYP2C9 (0.46) MEN1KMT2A
SCHEMBL9810600 0.78 CYP2C9 (0.46) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068389-A TERTIARY ALCOHOLS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed