Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.42 |
| ▸ | THRA | P10827 | 5/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810482 | 0.99 | THRB (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810330 | 0.99 | THRB (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810307 | 0.99 | THRB (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810460 | 0.98 | THRA (0.42) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810284 | 0.96 | THRA (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810477 | 0.96 | THRA (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810485 | 0.96 | THRA (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810387 | 0.96 | THRA (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810336 | 0.96 | THRA (0.43) | THRBTHRAOPRL1S1PR1S1PR3 | |
| SCHEMBL9810515 | 0.96 | THRA (0.43) | THRBTHRAOPRL1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |