Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9810941

Cc1cccc(C)c1C.N

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.58
ATM Q13315 1/20 0.58
TSHR P16473 3/20 0.53
ACHE P22303 2/20 0.53
CYP2A6 P11509 2/20 0.53
CYP1A2 P05177 2/20 0.53
ALDH1A1 P00352 4/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
RAPGEF4 Q8WZA2 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 3/20 0.43
CD44 P16070 1/20 0.43
HTR1B P28222 1/20 0.43
CYP3A4 P08684 2/20 0.42
PIK3CA P42336 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2017512 1.00 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
Bromide SCHEMBL27507502 0.96 TRPA1 (0.55) TRPA1ATMTSHRACHECYP2A6
Ammonia Solution, Strong SCHEMBL27819136 0.96 TRPA1 (0.55) TRPA1ATMTSHRACHECYP2A6
Ammonia Solution, Strong SCHEMBL27787866 0.96 TRPA1 (0.55) TRPA1ATMTSHRACHECYP2A6
Bromide SCHEMBL3447848 0.96 TRPA1 (0.55) TRPA1ATMTSHRACHECYP2A6
Hydrochloric Acid SCHEMBL13506528 0.96 TRPA1 (0.55) TRPA1ATMTSHRACHECYP2A6
SCHEMBL40704 0.96
SCHEMBL5494561 0.96 TRPA1 (0.61) TRPA1ATMTSHRACHECYP2A6
Methyl Alcohol SCHEMBL28192277 0.93 TRPA1 (0.60) TRPA1ATMTSHRACHECYP2A6
Bromide SCHEMBL21173634 0.92 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0279138-B1 FIBRES, YARNS, TEXTILE ARTICLES BASED ON POLYVINYL CHLORIDE WITH AN IMPROVED THERMAL RESISTANCE RHOVYL (FR) 1991-05-15 EP claimed
EP-0279139-A1 Flame-resistant chlorofibres and process for their manufacture RHOVYL (FR) 1988-08-24 EP claimed
CN-113039221-A Process for preparing poly-alpha-olefin terpolymer 埃克森美孚化学专利公司 2021-06-25 CN disclosed
CN-113015755-A Metallocene dimer selective catalyst and process for preparing poly-alpha-olefin dimers 埃克森美孚化学专利公司 2021-06-22 CN disclosed
CN-109414514-A Immunomodulator is imaged in PET 百时美施贵宝公司 2019-03-01 CN disclosed
CN-105358154-A Acc inhibitors and uses thereof NIMBUS APOLLO INC 2016-02-24 CN disclosed
CN-105358155-A Acc inhibitors and uses thereof NIMBUS APOLLO INC 2016-02-24 CN disclosed
CN-105358152-A Acc inhibitors and uses thereof NIMBUS APOLLO INC 2016-02-24 CN disclosed
CN-105358143-A Acc inhibitors and uses thereof NIMBUS APOLLO INC 2016-02-24 CN disclosed
EP-0279138-B1 FIBRES, YARNS, TEXTILE ARTICLES BASED ON POLYVINYL CHLORIDE WITH AN IMPROVED THERMAL RESISTANCE RHOVYL (FR) 1991-05-15 EP disclosed
EP-0279139-A1 Flame-resistant chlorofibres and process for their manufacture RHOVYL (FR) 1988-08-24 EP disclosed
EP-0279138-A1 Fibres, yarns, textile articles based on polyvinyl chloride with an improved thermal resistance RHOVYL (FR) 1988-08-24 EP disclosed
US-4421652-A CATION EXCHANGE RESIN OF SMALL PARTICLE SIZE FOR WATER PURICIATION FLUID POWER RESEARCH, INC. (US) 1983-12-20 US disclosed
US-4298468-A SUPPLYING REGENERANT FLUID TO ION EXCHANGE RESIN CLACK CORPORATION 1981-11-03 US disclosed
US-4239621-A WATER SOFTENING FLUID POWER RESEARCH, INC. (US) 1980-12-16 US disclosed
US-4238325-A Fluid treating apparatus and method FLUID POWER RESEARCH, INC. (US) 1980-12-09 US disclosed
US-3960721-A Fluid treating apparatus and method FLUID POWER RESEARCH, INC. (US) 1976-06-01 US disclosed