SCHEMBL5494561

SCHEMBL5494561

Cc1cccc(C)c1C.Cc1cccc(C)c1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.61
ATM Q13315 1/20 0.61
TSHR P16473 3/20 0.57
ACHE P22303 2/20 0.57
CYP2A6 P11509 2/20 0.56
CYP1A2 P05177 1/20 0.56
ALDH1A1 P00352 4/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
RAPGEF4 Q8WZA2 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CD44 P16070 1/20 0.45
MAPT P10636 3/20 0.44
CYP3A4 P08684 1/20 0.44
PIK3CA P42336 1/20 0.44
HTR1B P28222 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40704 1.00
SCHEMBL10941713 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
Water SCHEMBL11662813 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
SCHEMBL31498525 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
Ammonia Solution, Strong SCHEMBL9810941 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
Ammonia Solution, Strong SCHEMBL2017512 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
Hydrochloric Acid SCHEMBL22194330 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
Benzene SCHEMBL22829865 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
Bromide SCHEMBL21173634 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6
SCHEMBL7695351 0.96 TRPA1 (0.58) TRPA1ATMTSHRACHECYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105084497-A Treatment agent for removing trimethylbenzene in waste water in alkyd resin workshop WENZHOU HONGCHENGXIANG TECHNOLOGY CO LTD 2015-11-25 CN disclosed
CN-105060574-A Method of removing trimethylbenzene from workshop waste water of alkyd resin WENZHOU HONGCHENGXIANG TECHNOLOGY CO LTD 2015-11-18 CN disclosed
US-20120202766-A1 N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS PHARMASSET, INC. (US) 2012-08-09 US disclosed
CN-102304011-A Method for producing 1,2,4-trimethylbenzene by C9 aromatic hydrocarbon isomerization ZHENJIANG ZHENGDAN CHEMICAL INDUSTRY CO LTD 2012-01-04 CN disclosed
US-20070078080-A1 N4-Acylcytosine Nucleosides for Treatment of Viral Infections GILEAD PHARMASSET LLC 2007-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078080-A1 N4-Acylcytosine Nucleosides for Treatment of Viral Infections ENTPD5, DUT, NT5C3B TRPA1 4883/4885ATM 4780/4885TSHR 4176/4885
US-20120202766-A1 N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS ENTPD5, DUT, NT5C3B TRPA1 4883/4885ATM 4787/4885TSHR 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.