Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305957 | 0.90 | HSD17B10 (0.54) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL9811152 | 0.85 | POLB (0.46) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL9443129 | 0.84 | POLB (0.59) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL717957 | 0.83 | LMNA (0.63) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL9811169 | 0.82 | MAPT (0.58) | POLBMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL718296 | 0.81 | PPARA (0.67) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL11037389 | 0.79 | POLB (0.49) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL9811149 | 0.79 | PPARA (0.48) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL8972389 | 0.78 | HSD17B10 (0.51) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL9443126 | 0.78 | ALDH1A1 (0.54) | POLBMAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| EP-0161219-A2 | Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |