Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811159 | 0.89 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL10730209 | 0.87 | LMNA (0.53) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL14155832 | 0.85 | POLB (0.60) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL9443133 | 0.83 | POLB (0.58) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL9811151 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL9217591 | 0.82 | CYP2C9 (0.48) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL10643676 | 0.82 | POLB (0.54) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL10763852 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL10358900 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPK1POLBLMNA | |
| SCHEMBL9811040 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPK1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| US-4696763-A | PAINTS, BLENDS | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |
| US-4652653-A | Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio)-carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0161219-A2 | Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |