SCHEMBL9811218

SCHEMBL9811218

CCOC(=O)C(C)CSc1nc2ccccc2s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
HPGD P15428 2/20 0.59
APEX1 P27695 2/20 0.57
MAPT P10636 2/20 0.56
POLB P06746 3/20 0.56
RECQL P46063 1/20 0.56
ALOX5 P09917 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.52
MAPK1 P28482 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TSHR P16473 1/20 0.52
KMT2A Q03164 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C19 P33261 1/20 0.51
HIF1A Q16665 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
NPC1 O15118 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29023738 0.84 MAPT (0.66) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL10821618 0.84 APEX1 (0.62) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL10763608 0.83 ALDH1A1 (0.54) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL9811040 0.83 ALDH1A1 (0.55) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL10643298 0.83 APEX1 (0.61) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL14155832 0.83 POLB (0.60) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL10761742 0.82 MAPT (0.50) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL10359352 0.81 ALDH1A1 (0.57) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL10037466 0.81 APEX1 (0.64) ALDH1A1HPGDAPEX1MAPTPOLB
SCHEMBL9220907 0.81 ALDH1A1 (0.70) ALDH1A1HPGDAPEX1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161219-B1 HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
US-4696763-A PAINTS, BLENDS CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed