Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780861 | 0.87 | CYP3A4 (0.47) | ENPP2ADRA2CALOX15CYP3A4CASP1 | |
| SCHEMBL56105 | 0.87 | CYP3A4 (0.47) | ENPP2ADRA2CALOX15CYP3A4CASP1 | |
| Hydrochloric Acid SCHEMBL29955380 | 0.84 | CYP3A4 (0.46) | ENPP2ADRA2CALOX15CYP3A4CASP1 | |
| Water SCHEMBL4437578 | 0.84 | CYP3A4 (0.45) | ENPP2ADRA2CALOX15CYP3A4CASP1 | |
| Hydrochloric Acid SCHEMBL731024 | 0.84 | CYP3A4 (0.46) | ENPP2ADRA2CALOX15CYP3A4CASP1 | |
| Alcohol SCHEMBL29246863 | 0.78 | ENPP2 (0.45) | ENPP2ADRA2CALOX15CYP3A4CASP1 | |
| Sulfuric Acid SCHEMBL17580241 | 0.77 | GAA (0.41) | MEN1GAAKMT2AENPP2ALOX15 | |
| SCHEMBL3324879 | 0.77 | ENPP2 (0.39) | MEN1USP2GAAKMT2AENPP2 | |
| Bicarbonate SCHEMBL28659065 | 0.75 | ALDH1A1 (0.38) | GAAENPP2ADRA2CALOX15CYP3A4 | |
| Fluorene SCHEMBL28174324 | 0.75 | ALDH1A1 (0.47) | ADRA2CCYP3A4SMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194084-B1 | ELECTROCHEMICAL ASSAY FOR CIS-DIOLS | MediSense, Inc. (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4820636-A | Electrochemical assay for cis-diols | MEDISENSE, INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0194084-A2 | Electrochemical assay for cis-diols | MediSense, Inc. (US) | 1986-09-10 | — | — | EP | disclosed |