Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811417 | 1.00 | ALDH1A1 (0.40) | ALDH1A1EHMT2ELANEHSD11B1AGTR2 | |
| SCHEMBL9811411 | 1.00 | ALDH1A1 (0.40) | ALDH1A1EHMT2ELANEHSD11B1AGTR2 | |
| SCHEMBL9811337 | 0.81 | EHMT2 (0.42) | ALDH1A1EHMT2HSD11B1MEN1KMT2A | |
| SCHEMBL11028601 | 0.79 | EHMT2 (0.42) | EHMT2AGTR2MEN1KMT2A | |
| SCHEMBL9814365 | 0.79 | ELANE (0.41) | EHMT2ELANEAGTR2MEN1KMT2A | |
| SCHEMBL9811335 | 0.79 | ELANE (0.41) | EHMT2ELANEAGTR2MEN1KMT2A | |
| SCHEMBL9811457 | 0.78 | GHSR (0.40) | ALDH1A1EHMT2ELANEHSD11B1 | |
| SCHEMBL9811470 | 0.78 | GHSR (0.40) | ALDH1A1EHMT2ELANEHSD11B1 | |
| SCHEMBL9811450 | 0.78 | GHSR (0.40) | ALDH1A1EHMT2ELANEHSD11B1 | |
| SCHEMBL9811384 | 0.75 | EHMT2 (0.38) | ALDH1A1EHMT2ELANEHSD11B1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223588-B1 | PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0223588-A1 | Process for the preparation of beta-lactam compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-27 | — | — | EP | disclosed |