Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 14/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811492 | 1.00 | NAAA (0.65) | NAAACTSLASAH1ALDH1A1GAA | |
| SCHEMBL4079431 | 0.86 | NAAA (0.85) | NAAACTSLASAH1 | |
| SCHEMBL4073924 | 0.86 | NAAA (0.85) | NAAACTSLASAH1 | |
| SCHEMBL4073930 | 0.86 | NAAA (0.85) | NAAACTSLASAH1 | |
| SCHEMBL9811252 | 0.85 | NAAA (0.60) | NAAAASAH1ALDH1A1 | |
| SCHEMBL9811242 | 0.85 | NAAA (0.60) | NAAAASAH1ALDH1A1 | |
| SCHEMBL9811247 | 0.85 | NAAA (0.60) | NAAAASAH1ALDH1A1 | |
| SCHEMBL9811243 | 0.83 | NAAA (0.54) | NAAAASAH1 | |
| SCHEMBL9811239 | 0.83 | NAAA (0.54) | NAAAASAH1 | |
| SCHEMBL9811249 | 0.83 | NAAA (0.54) | NAAAASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202795-B1 | 4-SUBSTITUTED DIAZOLIDINONES | ELI LILLY AND COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4826993-A | Substituted diazolidinones | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0202795-A1 | 4-Substituted diazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-26 | — | — | EP | disclosed |