Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 15/20 | 0.54 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811243 | 1.00 | NAAA (0.54) | NAAAASAH1EPHX1DPP8DPP9 | |
| SCHEMBL9811239 | 1.00 | NAAA (0.54) | NAAAASAH1EPHX1DPP8DPP9 | |
| SCHEMBL9811485 | 0.83 | NAAA (0.65) | NAAAASAH1 | |
| SCHEMBL9811492 | 0.83 | NAAA (0.65) | NAAAASAH1 | |
| SCHEMBL9811247 | 0.81 | NAAA (0.60) | NAAAASAH1 | |
| SCHEMBL9811252 | 0.81 | NAAA (0.60) | NAAAASAH1 | |
| SCHEMBL9811242 | 0.81 | NAAA (0.60) | NAAAASAH1 | |
| SCHEMBL9668434 | 0.81 | ALDH1A1 (0.52) | NAAAASAH1EPHX1 | |
| Hydrochloric Acid SCHEMBL5723839 | 0.78 | EPHX1 (0.52) | NAAAEPHX1DPP8DPP9 | |
| SCHEMBL2299040 | 0.75 | IDO1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202795-B1 | 4-SUBSTITUTED DIAZOLIDINONES | ELI LILLY AND COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4826993-A | Substituted diazolidinones | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0202795-A1 | 4-Substituted diazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-26 | — | — | EP | disclosed |