Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41373 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL6551368 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL12143762 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL1332603 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL3925162 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL31420199 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL28376606 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL27882439 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL5853798 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL12144534 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431122-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| WO-1991000312-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-01-10 | — | — | WO | disclosed |