SCHEMBL41373

SCHEMBL41373

Cc1ccc(S(=O)(=O)C(O)(CO)S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
GAA P10253 2/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
MMP1 P03956 2/20 0.44
MMP9 P14780 2/20 0.44
MMP13 P45452 2/20 0.44
MMP2 P08253 1/20 0.44
MMP8 P22894 1/20 0.44
CA12 O43570 1/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853798 0.82 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL12143762 0.80 ALDH1A1 (0.53) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL9811491 0.79 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL31420199 0.78 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL28376606 0.78 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL20958158 0.76 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL10589227 0.76 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL12144534 0.74 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL30565133 0.73 GAA (0.59) ALDH1A1MEN1KMT2ACYP3A4CYP2C9
SCHEMBL31004986 0.73 ALDH1A1 (0.49) ALDH1A1MEN1KMT2ACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297157-B2 18F-labeled peptide ligands useful in PET and Cerenkov luminescene imaging CORNELL UNIVERSITY (US) 2025-05-13 US disclosed
EP-4249005-A2 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS Cornell University (US) 2023-09-27 EP disclosed
EP-3493856-B1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS UNIV CORNELL (US) 2023-08-09 EP disclosed
US-20220194904-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS CORNELL UNIVERSITY (US) 2022-06-23 US disclosed
US-20200317588-A1 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING CORNELL UNIVERSITY (US) 2020-10-08 US disclosed
EP-3176155-B1 1,2-BIS-(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND INTERMEDIATE FOR THE SYNTHESIS OF SAME CATEXEL LTD (GB) 2019-09-25 EP disclosed
EP-3493856-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS Cornell University (US) 2019-06-12 EP disclosed
WO-2018005625-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS CORNELL UNIVERSITY (US) 2018-01-04 WO disclosed
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS UNIV CORNELL (US) 2017-12-28 US disclosed
EP-3176155-A1 1,2-BIS-(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND INTERMEDIATE FOR THE SYNTHESIS OF SAME Catexel Limited (GB) 2017-06-07 EP disclosed
WO-2012003598-A1 INTERMEDIATES FOR THE SYNTHESIS OF 1,2-BIS(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND PREPARATION METHOD THEREOF UNILEVER PLC (GB) 2012-01-12 WO disclosed
WO-2012003599-A1 METHODS FOR THE SYNTHESIS OF BIS (TRIAZACYCLONONANE) LIGANDS UNILEVER PLC (GB) 2012-01-12 WO disclosed
EP-1729818-B8 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING CENTRE NAT RECH SCIENT (FR) 2010-02-17 EP disclosed
EP-1729818-B1 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING CENTRE NAT RECH SCIENT (FR) 2009-09-23 EP disclosed
US-20070218010-A1 Contrast Agents for Magnetic Resonance Imaging CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2007-09-20 US disclosed
EP-1729818-A2 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING Centre National de la Recherche Scientifique (CNRS) (FR) 2006-12-13 EP disclosed
WO-2005094903-A2 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2005-10-13 WO disclosed
US-4639365-A Gadolinium chelates as NMR contrast agents THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1987-01-27 US disclosed
EP-0198051-A1 GADOLINIUM CHELATES AS NMR CONTRAST AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1986-10-22 EP disclosed
WO-1986002352-A1 GADOLINIUM CHELATES AS NMR CONTRAST AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1986-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317588-A1 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING VIP, CALCA, GLP1R ALDH1A1 4664/4885MEN1 67/4885KMT2A 4516/4885
US-20070218010-A1 Contrast Agents for Magnetic Resonance Imaging MAG, SLC40A1, FABP7 ALDH1A1 2554/4885MEN1 12/4885KMT2A 1289/4885
US-12297157-B2 18F-labeled peptide ligands useful in PET and Cerenkov luminescene imaging VIP, CALCA, GLP1R ALDH1A1 4664/4885MEN1 67/4885KMT2A 4516/4885
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS PSMA3, FOLH1, PSMA1 ALDH1A1 1262/4885MEN1 107/4885KMT2A 1419/4885
US-20220194904-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS PSMA3, FOLH1, PSMA1 ALDH1A1 1262/4885MEN1 107/4885KMT2A 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.