Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807561 | 0.84 | MAP2K1 (0.54) | ALDH1A1SMN1; SMN2L3MBTL1RECQLMAP2K1 | |
| SCHEMBL23795785 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1RECQLMAP2K1 | |
| SCHEMBL9811610 | 0.78 | ALDH3A1 (0.49) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7079342 | 0.76 | L3MBTL1 (0.60) | ALDH1A1SMN1; SMN2L3MBTL1MAP2K1HDAC1 | |
| SCHEMBL9728919 | 0.74 | HDAC1 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1HDAC1HDAC6 | |
| SCHEMBL17988061 | 0.72 | MAP2K1 (0.55) | ALDH1A1SMN1; SMN2L3MBTL1MAP2K1PDK2 | |
| SCHEMBL11599081 | 0.72 | L3MBTL1 (0.64) | ALDH1A1SMN1; SMN2L3MBTL1RECQLMAP2K1 | |
| SCHEMBL9234372 | 0.72 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2L3MBTL1HDAC1HDAC6 | |
| SCHEMBL463590 | 0.71 | AR (0.62) | ALDH1A1SMN1; SMN2L3MBTL1MAP2K1KIF11 | |
| SCHEMBL5561662 | 0.71 | MAP2K1 (0.54) | ALDH1A1SMN1; SMN2L3MBTL1MAP2K1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3109362-A | — | — | None | — | — | JP | disclosed |
| JP-H03109362-A | FLUOROALKYL GROUP-CONTAINING AROMATIC NITROGEN COMPOUND AND PREPARATION THEREOF | NIPPON OIL & FATS CO LTD | 1991-05-09 | — | — | JP | disclosed |