Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.65 |
| ▸ | DYRK1B | Q9Y463 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3526528 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL981479 | 0.89 | ALDH1A1 (0.79) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL4950825 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL13163231 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL9490046 | 0.83 | KMT2A (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL980397 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPTCYP1A2F3 | |
| SCHEMBL17147752 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL20358014 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL27260229 | 0.79 | DYRK1A (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL9566863 | 0.79 | DYRK1A (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006052985-A1 | LACTONES AS NEW OXYGENATE FUEL ADDITIVES, FUELS BASED THEREON AND METHODS FOR USING SAME | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-05-18 | — | — | WO | claimed |
| US-20060096158-A1 | Lactones as new oxygenate fuel additives, fuels based thereon and methods for using same | ROBINSON J M | 2006-05-11 | — | — | US | claimed |
| US-3993771-A | FUNGICIDES; ALPHA-BENZYLIDINE-GAMMA-BUTYROLACTONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-23 | — | — | US | claimed |
| JP-61057572-A | — | — | None | — | — | JP | disclosed |
| JP-61057571-A | — | — | None | — | — | JP | disclosed |
| JP-55147204-A | — | — | None | — | — | JP | disclosed |
| EP-2709977-B1 | USE OF BENZOTROPOLONE DERIVATIVES AS PHOTOSTABILIZER AND ANTIOXIDANT FOR STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS. | BASF SE (DE) | 2018-09-05 | — | — | EP | disclosed |
| US-9663442-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2017-05-30 | — | — | US | disclosed |
| US-20150353470-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| US-9068080-B2 | Merocyanine derivatives | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |
| US-5231192-A | Reacting an a-acyl lactone, an aldehyde and an alkali metal hydroxide; hydrogenation | HENKEL CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| WO-1992010487-A1 | PROCESS FOR CONVERTING α-ACYL-SUBSTITUTED LACTONES TO α-ALKYLIDENE-SUBSTITUTED LACTONES | HENKEL CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992009590-A1 | PROCESS FOR THE PREPARATION OF α-ALKYL LACTONES | HENKEL CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |
| US-4980342-A | Process for the preparation of α-alkyl lactones | HENKEL CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| JP-S6157571-A | NOVEL ALPHA-BENZYLIDENE-GAMMA-BUTYROLACTONE DERIVATIVE | KANEGAFUCHI CHEM IND CO LTD | 1986-03-24 | — | — | JP | disclosed |
| JP-S6157572-A | NOVEL ALPHA-BENZYLIDENE-GAMMA-BUTYROLACTONE DERIVATIVE | KANEGAFUCHI CHEM IND CO LTD | 1986-03-24 | — | — | JP | disclosed |
| JP-S55147204-A | FUNGICIDE COMPOSITION FOR RICE CROP | SUMITOMO CHEM CO LTD | 1980-11-17 | — | — | JP | disclosed |
| US-3993771-A | FUNGICIDES; ALPHA-BENZYLIDINE-GAMMA-BUTYROLACTONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-23 | — | — | US | disclosed |
| US-3993771-A | FUNGICIDES; ALPHA-BENZYLIDINE-GAMMA-BUTYROLACTONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353470-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | CBR3, CBR1, CYP8B1 | ALDH1A1 2862/4885KMT2A 3226/4885DYRK1A 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.