Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.63 |
| ▸ | DYRK1B | Q9Y463 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | CLK1 | P49759 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147752 | 1.00 | ALDH1A1 (0.65) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL981190 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL3526528 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL9490046 | 0.78 | KMT2A (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL2869244 | 0.78 | CYP1A2 (0.86) | ALDH1A1KMT2AMAPTCYP1A2NPC1 | |
| SCHEMBL2868624 | 0.78 | CYP1A2 (0.86) | ALDH1A1KMT2AMAPTCYP1A2NPC1 | |
| SCHEMBL11966165 | 0.78 | CYP1A2 (0.86) | ALDH1A1KMT2AMAPTCYP1A2NPC1 | |
| SCHEMBL29099913 | 0.78 | CYP1A2 (0.86) | ALDH1A1KMT2AMAPTCYP1A2NPC1 | |
| SCHEMBL9566863 | 0.77 | DYRK1A (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT | |
| SCHEMBL27260229 | 0.77 | DYRK1A (1.00) | ALDH1A1KMT2ADYRK1ADYRK1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | claimed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | claimed |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | disclosed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | XPA, MEP1A, EED | ALDH1A1 107/4885KMT2A 1689/4885DYRK1A 4669/4885 |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | XPA, MEP1A, EED | ALDH1A1 107/4885KMT2A 1689/4885DYRK1A 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.