Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811915 | 1.00 | MAOB (0.50) | MAOBALOX5LTA4HABCB1LAP3 | |
| SCHEMBL9811926 | 1.00 | MAOB (0.50) | MAOBALOX5LTA4HABCB1LAP3 | |
| SCHEMBL9811980 | 0.94 | ABCB1 (0.42) | MAOBABCB1 | |
| SCHEMBL9811965 | 0.94 | ABCB1 (0.42) | MAOBABCB1 | |
| SCHEMBL9811991 | 0.94 | ABCB1 (0.42) | MAOBABCB1 | |
| SCHEMBL9811986 | 0.89 | ABCB1 (0.50) | MAOBABCB1 | |
| SCHEMBL9811979 | 0.89 | ABCB1 (0.50) | MAOBABCB1 | |
| SCHEMBL10528644 | 0.86 | ADRB2 (0.51) | MAOBALOX5 | |
| SCHEMBL10526893 | 0.86 | ADRB2 (0.51) | MAOBALOX5 | |
| SCHEMBL10528637 | 0.86 | ADRB2 (0.51) | MAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170121-B1 | 2-HYDROXY-3-ARYLOXYPROPYL OR 2-HYDROXY-2-BENZOFURANYL ETHYL TERTIARY AMINE HAVING AN ANTI-HYPERGLYCAEMIC AND/OR ANTI-OBESITY ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-06-19 | — | — | EP | disclosed |
| EP-0170121-A1 | 2-Hydroxy-3-aryloxypropyl or 2-hydroxy-2-benzofuranyl ethyl tertiary amine having an anti-hyperglycaemic and/or anti-obesity activity | BEECHAM GROUP PLC (GB) | 1986-02-05 | — | — | EP | disclosed |