Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921797 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL2235748 | 0.81 | C5AR1 (0.40) | ALDH1A1TDP1TSHRCYP1A2CYP2C19 | |
| SCHEMBL127344 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL1444328 | 0.80 | ESR1 (0.45) | ALDH1A1CYP3A4TDP1L3MBTL1TSHR | |
| SCHEMBL11237351 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP3A4MAPK1TSHRALOX15 | |
| SCHEMBL5498507 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10ESR1SMN1; SMN2 | |
| SCHEMBL11406187 | 0.77 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL6275564 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL6255892 | 0.77 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL7590353 | 0.75 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309652-B1 | HAIR DYE | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0193656-B1 | HAIR-DYEING COMPOSITION | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0309652-A2 | Hair dye | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0137524-B1 | HAIR DYEING COMPOSITIONS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1988-01-20 | — | — | EP | disclosed |
| US-4661115-A | Hair dyeing agents | RUETGERSWERKE AKTIENGESELLSCHAFT (DE) | 1987-04-28 | — | — | US | disclosed |
| EP-0193656-A2 | Hair-dyeing composition | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1986-09-10 | — | — | EP | disclosed |
| EP-0137524-A1 | Hair dyeing compositions | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-04-17 | — | — | EP | disclosed |