Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285160 | 0.92 | CYP3A4 (0.54) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL127344 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL9812129 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL6275564 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL6255892 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL11406187 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL7590353 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL8204834 | 0.77 | ALDH1A1 (0.67) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL6140286 | 0.76 | CYP3A4 (0.52) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL39946 | 0.75 | ESR1 (0.44) | ALDH1A1TSHRMAPTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287328-A1 | LUBRICATING COMPOSITION | AFTON CHEMICAL CORPORATION | 2008-11-20 | — | — | US | disclosed |
| US-20080139421-A1 | Lubricating Composition | AFTON CHEMICAL CORPORATION | 2008-06-12 | — | — | US | disclosed |
| US-20080139428-A1 | A synergistic oil additive of a 1H-benzotriazole compound, and a nitrogen-containing compound, e.g., diphenylamine, and not including an alkyl bis-3-amino-1,2,4-triazole; oxidation resistance; diesel engines, particularly medium speed having a part including silver; marine, turbine and power engines | AFTON CHEMICAL CORPORATION | 2008-06-12 | — | — | US | disclosed |
| US-20080139422-A1 | Lubricating Composition | AFTON CHEMICAL CORPORATION | 2008-06-12 | — | — | US | disclosed |
| US-20080139427-A1 | LUBRICATING COMPOSITION | HUTCHISON DAVID A | 2008-06-12 | — | — | US | disclosed |
| US-5831087-A | Macrocyclic imide compounds | HOECHST CELANESE CORP. | 1998-11-03 | — | — | US | disclosed |