⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781681 | 0.78 | — | — | |
| SCHEMBL12051900 | 0.74 | — | — | |
| SCHEMBL740669 | 0.65 | TSHR (0.46) | — | |
| SCHEMBL27809125 | 0.62 | ALDH1A1 (0.42) | — | |
| Chloromethane SCHEMBL10466167 | 0.61 | — | — | |
| SCHEMBL4666436 | 0.60 | TSHR (0.39) | — | |
| SCHEMBL31492348 | 0.60 | — | — | |
| SCHEMBL16859457 | 0.59 | — | — | |
| SCHEMBL895844 | 0.57 | — | — | |
| SCHEMBL11412977 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314778-B1 | SUBSTITUTED AROMATIC SILANE COMPOUNDS AND METHOD FOR PREPARATION OF SAME | Hughes Aircraft Company (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4916038-A | PROTECTIVE COATINGS | HUGHES AIRCRAFT COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4902368-A | CURED EPOXY RESIN | HUGHES AIRCRAFT COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4874643-A | EPOXYSILANE PROTECTIVE COATING | HUGHES AIRCRAFT COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| US-4861901-A | Substituted aromatic silane compounds and method for preparation of same | HUGHES AIRCRAFT COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0314778-A1 | SUBSTITUTED AROMATIC SILANE COMPOUNDS AND METHOD FOR PREPARATION OF SAME. | HUGHES AIRCRAFT CO (US) | 1989-05-10 | — | — | EP | disclosed |
| WO-1988008846-A1 | SUBSTITUTED AROMATIC SILANE COMPOUNDS AND METHOD FOR PREPARATION OF SAME | HUGHES AIRCRAFT COMPANY (US) | 1988-11-17 | — | — | WO | disclosed |