SCHEMBL740669

SCHEMBL740669

CC(C)(Cl)CCC(C)(C)Cl

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049364 0.88 TSHR (0.36) TSHR
SCHEMBL12418599 0.88 TSHR (0.36) TSHR
SCHEMBL9808403 0.88 TSHR (0.36) TSHR
SCHEMBL4666436 0.82 TSHR (0.39) TSHR
SCHEMBL28713347 0.82 ALDH1A1 (0.67) TSHRALDH1A1THRB
SCHEMBL10756606 0.79 TSHR (0.33) TSHR
SCHEMBL993354 0.79
SCHEMBL8463868 0.79
SCHEMBL3209857 0.79
SCHEMBL31266934 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119537-A PVDF-based composite membrane and preparation method thereof 重庆文理学院 2024-12-13 CN claimed
CN-117285437-B Bexarotene derivative, preparation method and application thereof, and anti-tumor drug 沈阳药科大学 2024-09-17 CN claimed
CN-117285437-A Bexarotene derivative, preparation method and application thereof, and anti-tumor drug 沈阳药科大学 2023-12-26 CN claimed
CN-112479918-B Synthesis method of retinoic acid derivative Am580 成都大学 2023-07-14 CN claimed
CN-114075125-A Long-chain alkyl fluorine-containing sulfonate ionic membrane compound for blocking water permeation of lithium-air battery 上海漫关越水处理有限公司 2022-02-22 CN claimed
CN-112479918-A Synthetic method of retinoid derivative Am580 成都大学 2021-03-12 CN claimed
EP-2004611-A1 PROCESS FOR PREPARING RETINOID COMPOUNDS F. Hoffmann-La Roche AG (CH) 2008-12-24 EP claimed
WO-2007113122-A1 PROCESS FOR PREPARING RETINOID COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2007-10-11 WO claimed
US-20070232810-A1 Process for preparing retinoid compounds ROCHE PALO ALTO LLC 2007-10-04 US claimed
EP-0436775-A2 New Polymers and copolymers and method and initiation system for their preparation Ceskoslovenska akademie ved (CS) 1991-07-17 EP claimed
US-3980724-A Dihalogenation of doubly branched alkanes SUN VENTURES, INC. (US) 1976-09-14 US claimed
US-12617880-B2 Compounds for use in catalyst compositions for the production of polyolefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-05 US disclosed
US-20260008740-A1 BEXAROTENE DERIVATIVES AND THEIR USE IN TREATING CANCER DJ Therapeutics LLC (US) 2026-01-08 US disclosed
US-12338214-B2 Bexarotene derivatives and their use in treating cancer DJ Therapeutics LLC (US) 2025-06-24 US disclosed
EP-4543430-A1 SYNTHESIS OF TETRAHYDRONAPHTHALENOLS AND USES THEREOF IO Therapeutics, Inc. (US) 2025-04-30 EP disclosed
US-4454341-A ANTITUMOR, SKIN DISORDERS SRI INTERNATIONAL (US) 1984-06-12 US disclosed
EP-0098591-A1 Heterocyclic compounds and rodenticides containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-01-18 EP disclosed
EP-0098546-A1 Novel aromatic musks FRITZSCHE DODGE & OLCOTT INC. (US) 1984-01-18 EP disclosed
US-4146576-A MANUFACTURE OF CARBON FIBRES COAL INDUSTRY (PATENTS) LIMITED (GB) 1979-03-27 US disclosed
US-3980724-A Dihalogenation of doubly branched alkanes SUN VENTURES, INC. (US) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617880-B2 Compounds for use in catalyst compositions for the production of polyolefins PRMT5, CBR3, MET TSHR 176/4885ALDH1A1 1762/4885THRB 597/4885
US-12338214-B2 Bexarotene derivatives and their use in treating cancer C3AR1, CXCR3, CCR7 TSHR 594/4885ALDH1A1 1553/4885THRB 2530/4885
US-20260008740-A1 BEXAROTENE DERIVATIVES AND THEIR USE IN TREATING CANCER CXCR3, CCR6, CCR9 TSHR 369/4885ALDH1A1 2561/4885THRB 1972/4885
US-20070232810-A1 Process for preparing retinoid compounds RARB, RARG, RARA TSHR 197/4885ALDH1A1 138/4885THRB 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.