Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 4/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045857 | 0.95 | LMNA (0.38) | DNM1CA2OPRM1LMNAFDPS | |
| SCHEMBL9812486 | 0.87 | LMNA (0.35) | DNM1CA2OPRM1LMNAFDPS | |
| SCHEMBL4692042 | 0.78 | TSHR (0.32) | TSHR | |
| SCHEMBL17787524 | 0.77 | CA2 (0.41) | DNM1CA2OPRM1LMNACA1 | |
| SCHEMBL27709456 | 0.77 | MAPT (0.38) | DNM1CA2LMNACA1FDPS | |
| SCHEMBL961380 | 0.76 | LMNA (0.41) | DNM1CA2OPRM1LMNAFDPS | |
| SCHEMBL28109817 | 0.76 | CA2 (0.32) | DNM1CA2FDPSTSHR | |
| SCHEMBL28426610 | 0.76 | CA2 (0.44) | DNM1CA2LMNACA1FDPS | |
| SCHEMBL13847959 | 0.74 | — | — | |
| SCHEMBL21722662 | 0.73 | MAPT (0.42) | DNM1CA2LMNACA1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416250-A2 | N-acylurea and O-acylisourea derivatives of hyaluronic acid | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1991-03-13 | — | — | EP | claimed |