Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812500 | 1.00 | ACE (0.53) | ACE | |
| Hydrochloric Acid SCHEMBL9740832 | 0.98 | ACE (0.52) | ACE | |
| Hydrochloric Acid SCHEMBL11001616 | 0.93 | ACE (0.48) | ACE | |
| SCHEMBL13062887 | 0.87 | NOTUM (0.47) | ACE | |
| SCHEMBL12507491 | 0.86 | CHRM2 (0.45) | ACE | |
| SCHEMBL9812655 | 0.85 | ACE (0.49) | ACE | |
| SCHEMBL9812649 | 0.85 | ACE (0.49) | ACE | |
| SCHEMBL9812654 | 0.84 | PRKCG (0.50) | ACE | |
| SCHEMBL2159859 | 0.84 | PRKCG (0.50) | ACE | |
| SCHEMBL27383276 | 0.83 | LMNA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197474-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE INDOLINE-2-CARBOXYLIC ACID | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4898822-A | Process for preparing optically active indoline-2-carboxylic acid | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0197474-A2 | Process for preparing optically active indoline-2-carboxylic acid | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-10-15 | — | — | EP | disclosed |