Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.50 |
| ▸ | CTSL | P07711 | 9/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797934 | 0.89 | CTSL (0.57) | CTSKCTSLIDO1TDO2CTSS | |
| SCHEMBL10628905 | 0.88 | CTSK (0.57) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6449041 | 0.85 | CYP1A2 (0.46) | CTSKCTSLIDO1TDO2CTSS | |
| SCHEMBL10631052 | 0.84 | CTSL (0.46) | CTSKCTSLIDO1TDO2CTSS | |
| SCHEMBL9810239 | 0.83 | CYP3A4 (0.55) | CTSKCTSLIDO1CTSSCTSB | |
| SCHEMBL10631022 | 0.83 | CTSK (0.45) | CTSKCTSLIDO1TDO2CTSS | |
| SCHEMBL10630975 | 0.83 | CTSK (0.45) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6454981 | 0.82 | CTSL (0.50) | CTSKCTSLCTSSCTSB | |
| SCHEMBL10633866 | 0.82 | CTSL (0.50) | CTSKCTSLCTSSCTSB | |
| SCHEMBL22144261 | 0.78 | CTSK (0.66) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282219-B1 | AMINOETHYLPHOSPHINIC ACID DERIVATIVES | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0282219-A1 | Aminoethylphosphinic acid derivatives | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |