Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812702 | 1.00 | TP53 (0.41) | TP53MAPTLMNAKDM1ATHRB | |
| SCHEMBL9812411 | 0.90 | HIF1A (0.39) | MAPTLMNATHRBRARARARB | |
| SCHEMBL9812415 | 0.90 | HIF1A (0.39) | MAPTLMNATHRBRARARARB | |
| SCHEMBL8045784 | 0.89 | CYP2C9 (0.42) | TP53MAPTLMNAKDM1AFASN | |
| SCHEMBL9812514 | 0.86 | HIF1A (0.41) | ALDH1A1HPGDKMT2ATACR3 | |
| SCHEMBL9812523 | 0.86 | HIF1A (0.41) | ALDH1A1HPGDKMT2ATACR3 | |
| SCHEMBL9812579 | 0.86 | MGLL (0.42) | MAPTMGLL | |
| SCHEMBL9812582 | 0.86 | MGLL (0.42) | MAPTMGLL | |
| SCHEMBL11033937 | 0.85 | MGLL (0.43) | TP53MAPTLMNAKDM1ARARA | |
| SCHEMBL9812538 | 0.85 | USP30 (0.44) | TP53KDM1ATHRBFASNMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219975-B1 | FLUOROPHENYLCYCLOHEXANE DERIVATIVE | Chisso Corporation (JP) | 1991-07-03 | — | — | EP | disclosed |
| US-4855076-A | Fluorophenylcyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-08 | — | — | US | disclosed |