Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791728 | 0.87 | MAOB (0.68) | APPMAOBCA1CA2CA9 | |
| SCHEMBL27001618 | 0.86 | MAOB (0.66) | APPMAOBCA1CA2CA9 | |
| SCHEMBL7818265 | 0.86 | APP (0.74) | APPMAOBCA2MITFEGFR | |
| SCHEMBL2242806 | 0.82 | MAOB (0.64) | APPMAOBCA1CA2CA9 | |
| SCHEMBL20208913 | 0.81 | ALOX5 (0.57) | APPMAOBCA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL2312742 | 0.81 | MAOB (0.62) | APPMAOBCA1CA2CA9 | |
| SCHEMBL3920685 | 0.79 | FLT3 (0.59) | APPMAOBCA2NPC1RAB9A | |
| SCHEMBL4659168 | 0.77 | MAOB (0.78) | MAOBCA1CA2CA9ALOX5 | |
| SCHEMBL584305 | 0.77 | SMN1; SMN2 (0.57) | MAOBCA1CA2CA9NCOA1 | |
| SCHEMBL4151225 | 0.76 | MAOB (0.66) | APPMAOBCA2EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264836-B1 | POLYIMIDES AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 1991-07-31 | — | — | EP | claimed |