Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018982 | 0.81 | CA2 (0.55) | FLT3CA2NPC1RAB9AMAPT | |
| SCHEMBL9812779 | 0.79 | APP (0.57) | CA2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12347 | 0.77 | ALDH1A1 (0.52) | CA2SMN1; SMN2MAOAALDH1A1CYP3A4 | |
| SCHEMBL14941118 | 0.77 | PIM1 (0.56) | CA2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15031527 | 0.77 | MAOB (0.55) | CA2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12778679 | 0.77 | FLT3 (0.55) | FLT3CA2NPC1RAB9AMAPT | |
| SCHEMBL19794945 | 0.77 | CA2 (0.50) | FLT3CA2NPC1APPCHRM2 | |
| SCHEMBL2790760 | 0.77 | DYRK1A (0.59) | FLT3CA2NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL2482195 | 0.76 | DYRK1A (0.58) | FLT3CA2NPC1RAB9AMAPT | |
| SCHEMBL3277732 | 0.74 | SMN1; SMN2 (0.63) | FLT3CA2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049420-B1 | THIENO[2,3-E]INDOLE DERIVATIVES AS NEW ANTITUMOR AGENTS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2019-05-15 | — | — | EP | disclosed |
| US-7537812-B2 | Aligning agent for liquid crystal and liquid-crystal alignment film obtained with the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070036915-A1 | Comprising at least one polymer selected from a polyamic acid and a soluble polyimide, diethylene glycol diethyl ether, and dipropylene glycol monomethyl ether; good coating film uniformity even when the drying temperature changes during formation of the coating film | MARIKO KUROSAKI ET AL | 2007-02-15 | — | — | US | disclosed |