Acetic Acid

Acetic Acid

SCHEMBL9812828

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nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
FFAR3 O14843 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
THRB P10828 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
ALDH2 P05091 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119068 0.98 LMNA (0.36) LMNAFFAR3ALDH1A1TDP1MMP1
SCHEMBL1650860 0.98 LMNA (0.36) LMNAFFAR3ALDH1A1TDP1MMP1
Hydrochloric Acid SCHEMBL4373156 0.95 LMNA (0.34) LMNAFFAR3ALDH1A1TDP1MMP1
SCHEMBL11587115 0.91 ALDH1A1 (0.32) LMNAFFAR3ALDH1A1TDP1MMP1
SCHEMBL6039622 0.90 LMNA (0.31) LMNAMMP1MMP2MMP3MMP8
Methacrylic Acid SCHEMBL15637276 0.90 LMNA (0.31) LMNAMMP1MMP2MMP3MMP8
SCHEMBL15233991 0.86
Benzoquinone SCHEMBL28904518 0.85 MIF (0.33) LMNAALDH1A1
Acrylamide SCHEMBL9628310 0.83 ALDH1A1 (0.38) ALDH1A1
SCHEMBL6143379 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4366864-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2024-05-15 EP claimed
WO-2023281209-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2023-01-12 WO claimed
EP-4366864-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2024-05-15 EP disclosed
WO-2023281209-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2023-01-12 WO disclosed
EP-0208421-B1 FLUOROPOLYMER COMPOSITIONS, THEIR PREPARATION AND USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-17 EP disclosed
EP-0208421-A2 Fluoropolymer compositions, their preparation and use E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-14 EP disclosed
US-4595518-A Oil and water repellency E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-17 US disclosed
US-4070283-A Controlled surface porosity particles and a method for their production E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-01-24 US disclosed