Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126348 | 0.98 | PGR (0.35) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL4373162 | 0.96 | PGR (0.34) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9801775 | 0.96 | PGR (0.34) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Chloromethane SCHEMBL27766783 | 0.96 | PGR (0.34) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL3264022 | 0.82 | PGR (0.32) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL894270 | 0.82 | PGR (0.32) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL3278812 | 0.79 | MMP1 (0.35) | GRIK1 | |
| SCHEMBL3819594 | 0.78 | EPHX2 (0.35) | GRIK1 | |
| SCHEMBL1275900 | 0.77 | KMT2A (0.33) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| Acetic Acid SCHEMBL6238307 | 0.77 | FFAR3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366864-A1 | METHOD FOR PRODUCING A MULTI-CAPILLARY LINING | SEPARATIVE (FR) | 2024-05-15 | — | — | EP | claimed |
| WO-2023281209-A1 | METHOD FOR PRODUCING A MULTI-CAPILLARY LINING | SEPARATIVE (FR) | 2023-01-12 | — | — | WO | claimed |
| EP-4366864-A1 | METHOD FOR PRODUCING A MULTI-CAPILLARY LINING | SEPARATIVE (FR) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023281209-A1 | METHOD FOR PRODUCING A MULTI-CAPILLARY LINING | SEPARATIVE (FR) | 2023-01-12 | — | — | WO | disclosed |
| EP-0208421-B1 | FLUOROPOLYMER COMPOSITIONS, THEIR PREPARATION AND USE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-17 | — | — | EP | disclosed |
| EP-0208421-A2 | Fluoropolymer compositions, their preparation and use | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-14 | — | — | EP | disclosed |
| US-4595518-A | Oil and water repellency | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-06-17 | — | — | US | disclosed |