Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100881 | 0.86 | MEN1 (0.66) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL8358410 | 0.85 | MEN1 (0.68) | KMT2AMEN1HDAC2HDAC8HDAC6 | |
| SCHEMBL5681767 | 0.84 | RAB9A (0.73) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL9329695 | 0.82 | HTT (0.54) | SMN1; SMN2MAPTPPARGPPARAPTGDR2 | |
| SCHEMBL3578191 | 0.82 | KMT2A (0.56) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL3577619 | 0.81 | TRPV1 (0.69) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL10160158 | 0.79 | KDM4E (0.66) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL2769715 | 0.79 | PPARA (0.74) | MAPK1PPARGPPARAPTGDR2 | |
| SCHEMBL13477505 | 0.78 | PPARA (0.58) | MAPK1PPARGPPARAPTGDR2 | |
| SCHEMBL5178206 | 0.78 | RAB9A (0.69) | KMT2AMEN1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |